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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
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Affinity Data
Ki: 0.120nM
Assay Description:
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
Similars
In Depth
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Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.126nM
Assay Description:
Displacement of [3H]cytisine from nAChR alpha4beta2 in rat brain membrane
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.130nM
Assay Description:
Displacement of [3H]cytisine from nAChR alpha4beta2 in rat brain membrane
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 51nM
Assay Description:
Displacement of [3H]A585539 from alpha7 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at human nAChR alpha4beta2 receptor expressed in human HEK293 cells assessed as calcium flux by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.47E+3nM
Assay Description:
Agonist activity at human recombinant alpha7 nicotinic acetylcholine receptor expressed in xenopus laevis oocytes by parallel oocyte electrophysiolog...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 40nM
Assay Description:
Agonist activity at human recombinant alpha4beta2 nicotinic acetylcholine receptor expressed in HEK293 cells assessed as changes in intracellular cal...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50279369
(CHEMBL460562 | cis-2-(3-Pyridinyl)octahydropyrrolo...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at human nAChR alpha4beta2 receptor expressed in human HEK293 cells assessed as calcium flux by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI