Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257890(3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane | ...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Neuroscience Research

Curated by ChEMBL
LigandPNGBDBM50224466((1R,5R)-3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]he...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at recombinant human alpha-4-beta-2 nAChR expressed in HEK293 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Neuroscience Research

Curated by ChEMBL
LigandPNGBDBM50224462((1S,5S)-3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]he...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at recombinant human alpha-4-beta-2 nAChR expressed in HEK293 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257890(3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane | ...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human recombinant alpha4beta2 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50257890(3-(pyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane | ...)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at human recombinant alpha3beta4 nAChR expressed in human IMR32 cells assessed as calcium dynamics by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed