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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50393243
(CHEMBL2151437)
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Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Binding affinity to human alpha7 nAchR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50393243
(CHEMBL2151437)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes after 2 hrs by topcount scintillation counting an...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50393243
(CHEMBL2151437)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes after 2 hrs by topcount scintillation counting anal...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50393243
(CHEMBL2151437)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Binding affinity to human 5HT3A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50393243
(CHEMBL2151437)
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Copy InChI
Affinity Data
Ki: 140nM
Assay Description:
Binding affinity to human alpha4beta2 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Targacept
Curated by
ChEMBL
Ligand
BDBM50393243
(CHEMBL2151437)
Copy SMILES
Copy InChI
Affinity Data
EC50: 340nM
Assay Description:
Agonist activity at human alpha7 nAChR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI