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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
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Affinity Data
Ki: 4.80nM
Assay Description:
Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
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Copy InChI
Affinity Data
EC50: 5.30nM
Assay Description:
Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2nM
Assay Description:
Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
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Affinity Data
EC50: 0.930nM
Assay Description:
Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.600nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...
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Target Info
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Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...
More data for this Ligand-Target Pair
Target Info
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Target
Free fatty acid receptor 1
(Mus musculus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563848
(CHEMBL4782004)
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Affinity Data
EC50: 0.460nM
Assay Description:
Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
Purchase
PC cid
PC sid
In Depth
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Article
PubMed
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