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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563850
(CHEMBL4795763)
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Affinity Data
Ki: 130nM
Assay Description:
Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563850
(CHEMBL4795763)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Mus musculus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563850
(CHEMBL4795763)
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Affinity Data
EC50: 7.20nM
Assay Description:
Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563850
(CHEMBL4795763)
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Affinity Data
EC50: 23nM
Assay Description:
Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563850
(CHEMBL4795763)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.80nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563850
(CHEMBL4795763)
Copy SMILES
Copy InChI
Affinity Data
EC50: 84nM
Assay Description:
Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI