Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL

LigandBDBM50236691(CHEMBL4080911)Copy SMILESCopy InChI

Affinity DataEC50:  240nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL

LigandBDBM50236692(CHEMBL4066238)Copy SMILESCopy InChI

Affinity DataEC50:  81nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetFree fatty acid receptor 4(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL

LigandBDBM50236692(CHEMBL4066238)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR120 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL

LigandBDBM50236692(CHEMBL4066238)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL

LigandBDBM50236693(CHEMBL4088797)Copy SMILESCopy InChI

Affinity DataEC50:  410nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI