Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM293969
((2S)-5-(2-(4-((3-(2- Methylphenyl)benzo[b]thiophen...)
Copy SMILES
Affinity Data
EC50: 2nM
T: 2°C
Assay Description:
Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM294029
((2S)-5-(2-(4-((3-(2- Methylphenyl)benzo[b]thiophen...)
Copy SMILES
Affinity Data
EC50: 34nM
T: 2°C
Assay Description:
Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM293969
((2S)-5-(2-(4-((3-(2- Methylphenyl)benzo[b]thiophen...)
Copy SMILES
Affinity Data
EC50: 9nM
Assay Description:
Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Rattus norvegicus)
TBA
Ligand
BDBM293969
((2S)-5-(2-(4-((3-(2- Methylphenyl)benzo[b]thiophen...)
Copy SMILES
Affinity Data
EC50: 7nM
Assay Description:
Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM294030
((2S)-5-(2-(4-((3-(2- Methylphenyl)benzo[b]thiophen...)
Copy SMILES
Affinity Data
EC50: 910nM
T: 2°C
Assay Description:
Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI