Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 2(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent

LigandBDBM476661((S)-6-(3-Chloro-5-(prop-1-yn-1-yl)- 1H-indol-2-yl)...)Copy SMILES

Affinity DataIC50:  24nMAssay Description:A BACE2 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected compounds by AnaSpec BACE2 fluorescent as...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent

LigandBDBM476661((S)-6-(3-Chloro-5-(prop-1-yn-1-yl)- 1H-indol-2-yl)...)Copy SMILES

Affinity DataIC50:  44nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI