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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Carbonic anhydrase 4
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 1.45E+4nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase IV
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Target
Monocarboxylate transporter 2
(Rattus norvegicus)
Physiologisch-Chemisches Institut Der Eberhard-Karls-Universit£T T£Bingen
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
Ki: 8.00E+4nM
Assay Description:
TP_TRANSPORTER: inhibition of lactate uptake in Xenopus laevis oocytes
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Target
Carbonic anhydrase
(Candida albicans (Yeast))
Università
Curated by
ChEMBL
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 1.06E+5nM
Assay Description:
Inhibition of Candida albicans Nce103
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Target
Solute carrier family 22 member 20
(Mus musculus)
University Of California
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
Ki: 2.71E+5nM
Assay Description:
Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr
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Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 1.12E+6nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase IX
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 2.11E+6nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase II
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 2.11E+6nM
Assay Description:
Inhibition of human carbonic anhydrase2
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Target
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 5.50E+6nM
Assay Description:
Binding affinity against human cytosolic Carbonic anhydrase V
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Target
Oxaloacetate decarboxylase
(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Maryland Biotechnology Institute
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: 7.20E+6nM
Assay Description:
Competitive inhibition constant determined for PA4872 catalyzed oxaloacetate decarboxylation.
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Target
Carbonic anhydrase [110-330]
(Flaveria bidentis (Coastal plain yellowtops))
Istituto Di Biostrutture E Bioimmagini-Cnr
Ligand
BDBM50159792
(CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...)
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Affinity Data
Ki: >1.00E+7nM ΔG°: >-11.2kJ/mole
pH: 8.3 T: 2°C
Assay Description:
Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C.
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Target
Solute carrier family 22 member 6
(Mus musculus)
University Of California
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
Ki: 1.19E+7nM
Assay Description:
Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr
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Target
Solute carrier organic anion transporter family member 2A1
(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
Ki: 2.60E+7nM
Assay Description:
TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells
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Target
C-terminal-binding protein 2
(Homo sapiens (Human))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
IC50: >3.00E+5nM
Assay Description:
Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...
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Target
Prolyl 4-hydroxylase
(Paramecium bursaria Chlorella virus 1)
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...
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Target Info
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Target
Alpha-ketoglutarate-dependent dioxygenase FTO
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM19473
(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...
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