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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Gamma-aminobutyric acid receptor subunit alpha-1
(Rattus norvegicus (Rat))
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
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Affinity Data
Ki: 17.5nM
More data for this Ligand-Target Pair
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PubMed
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Target
Gamma-aminobutyric acid receptor subunit alpha-3
(RAT)
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
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Affinity Data
Ki: 20nM
More data for this Ligand-Target Pair
Target Info
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Target
Gamma-aminobutyric acid receptor subunit alpha-5
(RAT)
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
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Affinity Data
Ki: 21nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Gamma-aminobutyric acid receptor subunit alpha-2
(Rattus norvegicus (Rat))
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
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Affinity Data
Ki: 41nM
More data for this Ligand-Target Pair
Target Info
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Target
Gamma-aminobutyric acid receptor subunit alpha-6
(RAT)
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
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Affinity Data
Ki: 51nM
More data for this Ligand-Target Pair
Target Info
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Target
Gamma-aminobutyric acid receptor subunit alpha-6
(RAT)
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10E+3nM
More data for this Ligand-Target Pair
Target Info
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Target
Gamma-aminobutyric acid receptor subunit alpha-4
(Rattus norvegicus (Rat))
Cocensys
Curated by
PDSP K
i
Database
Ligand
BDBM50045050
(1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
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Affinity Data
Ki: 1.90E+3nM
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Target
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat))
Research Triangle Institute
US Patent
Ligand
BDBM50055912
((3alpha,5alpha)-3-hydroxypregnan-20-one) | 1-((3R,...)
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Affinity Data
IC50: 12.6nM
Assay Description:
[35S]TBPS binding assay.
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Target
Glucose-6-phosphate 1-dehydrogenase
(Homo sapiens (Human))
University Of Manchester
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
IC50: 6.60E+4nM
Assay Description:
Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...
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ChEBI
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Target
Gamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta
(Homo sapiens (Human))
Sage Therapeutics
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
EC50: 76nM
Assay Description:
Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-med...
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3D Structure (crystal)
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Target
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2
(Homo sapiens (Human))
Cocensys
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
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Affinity Data
EC50: 160nM
Assay Description:
Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor
More data for this Ligand-Target Pair
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ChEBI
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3D Structure (crystal)
Copy BDB DOI
Target
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2
(Homo sapiens (Human))
Cocensys
Curated by
ChEMBL
Ligand
BDBM50191342
(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 237nM
Assay Description:
Inhibition of human ERG by patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI