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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Cathepsin S
(Homo sapiens (Human))
Novartis
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
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Affinity Data
IC50: 9nM
pH: 7.0 T: 2°C
Assay Description:
The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Novartis
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of human recombinant cathepsin S by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Mus musculus (Mouse))
Novartis
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
pH: 7.0 T: 2°C
Assay Description:
The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
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Copy InChI
Affinity Data
IC50: >1.50E+3nM
Assay Description:
Inhibition of human recombinant cathepsin K by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.65E+3nM
pH: 7.0 T: 2°C
Assay Description:
The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >4.00E+3nM
Assay Description:
Inhibition of human recombinant cathepsin L by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.20E+3nM
Assay Description:
The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Rattus norvegicus)
Novartis
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
pH: 7.0 T: 2°C
Assay Description:
The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Rattus norvegicus)
Novartis
Ligand
BDBM25134
(2-cyano-pyrropyrimidine, 2 | 7-(2-cyclohexylethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI