Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone deacetylase 3(Homo sapiens (Human))
The Broad Institute

US Patent

LigandBDBM559887(US11377423, Compound 12)Copy SMILESCopy InChI

Affinity DataIC50:  84nMMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent

LigandBDBM559887(US11377423, Compound 12)Copy SMILESCopy InChI

Affinity DataIC50:  90nMAssay Description:The following non-trypsin coupled in-vitro HDAC enzymatic endpoint assay was used to assay the compounds of the invention. Below is a standardized pr...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent

LigandBDBM559887(US11377423, Compound 12)Copy SMILESCopy InChI

Affinity DataIC50:  304nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI