Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Clermont Universite£

Curated by ChEMBL

LigandBDBM50347814(CHEMBL1802391)Copy SMILESCopy InChI

Affinity DataIC50:  87nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Clermont Universite£

Curated by ChEMBL

LigandBDBM50347814(CHEMBL1802391)Copy SMILESCopy InChI

Affinity DataIC50:  190nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Clermont Universite£

Curated by ChEMBL

LigandBDBM50347814(CHEMBL1802391)Copy SMILESCopy InChI

Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using Histone H1 and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI