Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute of Harvard and Mit

LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)
Affinity DataIC50:  106nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute of Harvard and Mit

LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)
Affinity DataIC50:  106nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)
Affinity DataIC50:  153nMAssay Description:The following non-trypsin coupled in-vitro HDAC enzymatic endpoint assay was used to assay the compounds of the invention. Below is a standardized pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)
Affinity DataIC50:  153nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)
Affinity DataIC50:  479nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM178097(4-Acetamido-N-(2-amino-5-fluorophenyl)benzamide (7...)
Affinity DataIC50:  479nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed