Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50535176(CHEMBL4544116)Copy SMILESCopy InChI

Affinity DataIC50:  16nMAssay Description:Inhibition of FITC-9mer Nrf2 peptide interaction with human recombinant Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli DE3 ce...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50535176(CHEMBL4544116)Copy SMILESCopy InChI

Affinity DataIC50:  16nMAssay Description:Inhibition of Keap1 Kelch domain/FITC-9mer Nrf2 (unknown origin) interaction after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI