Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 15 hits in this display   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  1.60nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  1.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  5.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 8/9(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  12nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  24nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  32nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:In vitro for inhibition of Dipeptidylpeptidase IV.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  88nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  1.60E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  1.90E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  5.10E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 8/9(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetHomeobox protein PKNOX1(Human)
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  2.40E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  3.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees of Tufts College

US Patent

LigandBDBM50050520(Boronic acid derivative | CHEMBL63406 | US11096924...)Copy SMILESCopy InChI

Affinity DataIC50:  8.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI