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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
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Affinity Data
Ki: 10.2nM ΔG°: -45.6kJ/mole
pH: 7.4 T: 2°C
Assay Description:
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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PC sid
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US Patent
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Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
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Affinity Data
IC50: 0.120nM
Assay Description:
Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-methylthio-ADP-induced calcium flux by FLIPR assay
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Target Info
PDB
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CHEMBL
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Article
PubMed
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Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.120nM
Assay Description:
Antagonist activity at human P2Y1 by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
PubMed
Copy BDB DOI
Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.120nM
Assay Description:
Inhibition of human P2Y1 by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
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PubMed
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Target
P2Y purinoceptor 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 10 uM ADP-induced platelet aggregation preincubated for 1 min foll...
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Target Info
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antibodypedia
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In Depth
Details
Article
PubMed
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Target
Phospholipase A2, membrane associated
(Homo sapiens (Human))
TBA
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
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Affinity Data
IC50: 180nM
Assay Description:
Antagonist activity at human pA2 by FLIPR assay
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Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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PubMed
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Target
P2Y purinoceptor 12
(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by
ChEMBL
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Antagonist activity at P2Y12 receptor (unknown origin)
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Article
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Target
P2Y purinoceptor 2
(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by
ChEMBL
Ligand
BDBM50045597
(CHEMBL3314321 | US9428504, 152)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Antagonist activity at P2Y2 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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