Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataKi:  10.2nM ΔG°:  -45.6kJ/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50:  0.120nMAssay Description:Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-methylthio-ADP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50:  0.120nMAssay Description:Antagonist activity at human P2Y1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human P2Y1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 10 uM ADP-induced platelet aggregation preincubated for 1 min foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))TBA
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human pA2 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50045597(CHEMBL3314321 | US9428504, 152)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at P2Y2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed