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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histamine H4 receptor
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM335440
((2,2-Dimethyl-propyl)-(4-piperazin-1-yl-pyrimidin-...)
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Affinity Data
Ki: 39nM
Assay Description:
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM335440
((2,2-Dimethyl-propyl)-(4-piperazin-1-yl-pyrimidin-...)
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Affinity Data
Ki: 186nM
Assay Description:
Displacement of 10 nM [3H]-histamine from human H4R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H2 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM335440
((2,2-Dimethyl-propyl)-(4-piperazin-1-yl-pyrimidin-...)
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Affinity Data
Ki: <1.00E+4nM
Assay Description:
Displacement of 5 nM [3H-pyrilamine from human H1R expressed in Sf9 cell membranes co-expressing RGS4 by competition binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H3 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM335440
((2,2-Dimethyl-propyl)-(4-piperazin-1-yl-pyrimidin-...)
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Affinity Data
Ki: <1.00E+4nM
Assay Description:
Displacement of 3 nM [3H]Nalpha-methylhistamine from human H3R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition bind...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H2 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM335440
((2,2-Dimethyl-propyl)-(4-piperazin-1-yl-pyrimidin-...)
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Copy InChI
Affinity Data
Ki: <1.00E+4nM
Assay Description:
Displacement of 20 nM [3H]UR-DE257 from human H2R expressed in Sf9 cell membranes co-expressing GsalphaS by competition binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI