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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Pirin
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50507431
(CHEMBL4473676 | US9701664, Example 191)
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Affinity Data
IC50: 33nM
Assay Description:
Displacement of 6-amino-9-(2-((4-((2-((6-((5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)carbamoyl)quinolin-2-yl)oxy)ethyl)amino)-...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Heat shock factor protein 1
(Homo sapiens (Human))
Cancer Research Technology
US Patent
Ligand
BDBM50507431
(CHEMBL4473676 | US9701664, Example 191)
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Affinity Data
IC50: 134nM
Assay Description:
U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50507431
(CHEMBL4473676 | US9701664, Example 191)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human full length GST-tagged BRAF expressed in baculovirus expression system
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI