Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

LigandBDBM50027879(CGP-12177 | CHEBI:73288)Copy SMILESCopy InChI

Affinity DataEC50:  12nMAssay Description:Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
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TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50027879(CGP-12177 | CHEBI:73288)Copy SMILESCopy InChI

Affinity DataKd:  19nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50027879(CGP-12177 | CHEBI:73288)Copy SMILESCopy InChI

Affinity DataKd:  0.200nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50027879(CGP-12177 | CHEBI:73288)Copy SMILESCopy InChI

Affinity DataKd:  0.200nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50027879(CGP-12177 | CHEBI:73288)Copy SMILESCopy InChI

Affinity DataKd:  19nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI