Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50134917(CHEMBL3747766)Copy SMILESCopy InChI

Affinity DataIC50:  120nMAssay Description:Inhibition of BACE1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50134917(CHEMBL3747766)Copy SMILESCopy InChI

Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of BACE1 in human PC12 cells expressing APP Sweden mutantMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 2(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50134917(CHEMBL3747766)Copy SMILESCopy InChI

Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50134917(CHEMBL3747766)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI