Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL

LigandBDBM50290995(CHEMBL321444 | N'-Benzyl-N'-[2-(1-formyl-4-guanidi...)Copy SMILESCopy InChI

Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for its 50% inhibitory concentration against cow protease enzyme trypsinMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50290995(CHEMBL321444 | N'-Benzyl-N'-[2-(1-formyl-4-guanidi...)Copy SMILESCopy InChI

Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for its 50 percent inhibitory concentration against human thrombin factor (FIIa)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetCoagulation factor VII(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50290995(CHEMBL321444 | N'-Benzyl-N'-[2-(1-formyl-4-guanidi...)Copy SMILESCopy InChI

Affinity DataIC50: >2.50E+4nMAssay Description:Compound was evaluated for its 50 percent inhibitory concentration against human Coagulation factor VIIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI