Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.00200nM
Assay Description:
Inhibition of HDAC6 (unknown origin) after 17 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.420nM
Assay Description:
Inhibition of HDAC3 (unknown origin) after 17 hrs
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.20nM
Assay Description:
Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of recombinant human N-terminal GST tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys (Ac)-AMC as subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of recombinant human HDAC6 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 6
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase
(Homo sapiens (Human))
Southern Medical University
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
Assay Description:
Inhibition of HDAC in human HeLa nuclear extracts using fluorometric substrate incubated for 30 mins by fluorescence plate reader analysis
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90.7nM
Assay Description:
Inhibition of HDAC10 (unknown origin) after 17 hrs
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 190nM
Assay Description:
Inhibition of HDAC3 (unknown origin) using carboxyfluorescein (FAM)-labeled acetylated peptide as substrate after 17 hrs by fluorescence-based electr...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 2
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 252nM
Assay Description:
Inhibition of HDAC2 (unknown origin) after 17 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 260nM
Assay Description:
Inhibition of recombinant human HDAC1 expressed in baculovirus expression system using Ac-Leu-Gly-Lys (Ac)-AMC as substrate preincubated for 5 mins f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 271nM
Assay Description:
Inhibition of HDAC1 (unknown origin) after 17 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 316nM
Assay Description:
Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 340nM
Assay Description:
Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 3
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 760nM
Assay Description:
Inhibition of recombinant human His-tagged HDAC3 expressed in baculovirus insect cells using Ac-Leu-Gly-Lys (Ac)-AMC as substrate preincubated for 5 ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 794nM
Assay Description:
Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 1
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.57E+3nM
Assay Description:
Inhibition of recombinant human HDAC1 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Southern Medical University
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.21E+3nM
Assay Description:
Inhibition of full length recombinant human C-terminal His tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-GlyLys (Tfa)-...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histone deacetylase 8
(Homo sapiens (Human))
Southern Medical University
Curated by
ChEMBL
Ligand
BDBM50261816
(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.85E+3nM
Assay Description:
Inhibition of HDAC8 (unknown origin) after 17 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI