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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
30
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Target
Histamine H3 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
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Affinity Data
Ki: 0.170nM
Assay Description:
Displacement of [3H[N-alpha-methylhistamine form human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation co...
More data for this Ligand-Target Pair
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Target
Histamine H3 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.430nM
Assay Description:
Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
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Target
Histamine H3 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.430nM
Assay Description:
Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...
More data for this Ligand-Target Pair
Target Info
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10nM
Assay Description:
Inhibition of human recombinant histamine H4 receptor expressed in CHO cells
More data for this Ligand-Target Pair
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10nM
Assay Description:
Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of 5HT2A receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
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Article
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Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of dopamine D1 receptor
More data for this Ligand-Target Pair
Target Info
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of dopamine D2 receptor
More data for this Ligand-Target Pair
Target Info
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of dopamine D3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
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Article
PubMed
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Target
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
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Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of muscarinic M3 receptor
More data for this Ligand-Target Pair
Target Info
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Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of muscarinic M1 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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Article
PubMed
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Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of beta-1 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
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Article
PubMed
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Target
Histamine H2 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of histamine H2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of histamine H1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Inhibition of beta2 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H2 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Displacement of [125I]aminopotentidine from human histamine H2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Displacement of [3H]rilamine from human histamine H1 receptor expressed in CHO cells after 1 hr by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.5nM
Assay Description:
Inhibition of human CYP2C19 expressed in insect cell microsome after 30 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.5nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
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Affinity Data
IC50: 470nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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Ligand Info
CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Inhibition of human CYP3A4 expressed in insect cell microsome after 30 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
Inhibition of human CYP1A2 expressed in insect cell microsome after 15 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
Inhibition of human CYP2D6 expressed in insect cell microsome after 30 mins by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.75nM
Assay Description:
Agonist activity at human recombinant histamine H3 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintillat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.75nM
Assay Description:
Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H3 receptor
(Homo sapiens (Human))
Meiji Seika Kaisha
Curated by
ChEMBL
Ligand
BDBM50317865
(2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole |...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.75nM
Assay Description:
Agonist activity at human histamine H3 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI