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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Rap guanine nucleotide exchange factor 3
(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Ligand
BDBM517701
(US11124489, Entry 15 | ZL0479)
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Affinity Data
IC50: 5.50E+3nM
Assay Description:
To explore the SARs and examine how the modifications on the isoxazole ring affect biological activities of newly synthesized analogues, we first eva...
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Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Rap guanine nucleotide exchange factor 4
(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Ligand
BDBM517701
(US11124489, Entry 15 | ZL0479)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30E+3nM
Assay Description:
From the biological results discussed above, compounds 10, 14-15, 23-24, 26-27, and 31-32 were identified as potent EPAC1 inhibitors with IC50 values...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI