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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Cyclin-A1/Cyclin-dependent kinase 2
(Homo sapiens (Human))
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM50539921
(CHEMBL4649802 | US11142507, Compound MFH-2-25-1)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human full-length N-terminal GST-tagged CDK2/cyclinA1 expressed in baculovirus infected Sf9 insect cells using FRET-labeled...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7
(Homo sapiens (Human))
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM50539921
(CHEMBL4649802 | US11142507, Compound MFH-2-25-1)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human full-length His-tagged CDK7/Cyclin H/MNAT1 expressed in baculovirus infection system using Cdk7/9tide as substrate me...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 9
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50539921
(CHEMBL4649802 | US11142507, Compound MFH-2-25-1)
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Affinity Data
IC50: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50539921
(CHEMBL4649802 | US11142507, Compound MFH-2-25-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Jurkat cells were treated with DMSO or concentration of compound indicated. 6 hours after treatment, cells were washed and harvested by resuspending ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cyclin-dependent kinase 7
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50539921
(CHEMBL4649802 | US11142507, Compound MFH-2-25-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human))
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM50539921
(CHEMBL4649802 | US11142507, Compound MFH-2-25-1)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human full-length His-tagged CDK9/Cyclin T1 expressed in baculovirus infection system using Cdk7/9tide as substrate measure...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI