Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50065390(CHEMBL3401341)Copy SMILESCopy InChI

Affinity DataKi:  56nMAssay Description:Inhibition of renin (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50065390(CHEMBL3401341)Copy SMILESCopy InChI

Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of CathD (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50065390(CHEMBL3401341)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI