Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL

LigandBDBM50307352(CHEMBL591478 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)Copy SMILESCopy InChI

Affinity DataKi:  3.30nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL

LigandBDBM50307352(CHEMBL591478 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)Copy SMILESCopy InChI

Affinity DataKi:  130nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI