Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL

LigandBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)Copy SMILESCopy InChI

Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL

LigandBDBM50297936(2-Hydroxy-2-phenethyl-pentanedioic acid 5-{[3-(met...)Copy SMILESCopy InChI

Affinity DataIC50:  230nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Swedish mutant sequence Eu-EVNLDAEFK-Quencher substrate by homogeneous time r...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI