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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50498210
(CHEMBL3423015)
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Affinity Data
Ki: 540nM
Assay Description:
Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50498210
(CHEMBL3423015)
Copy SMILES
Copy InChI
Affinity Data
Ki: 800nM
Assay Description:
Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells by fluorescence polariza...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50498210
(CHEMBL3423015)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.50E+4nM
Assay Description:
Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as thermal stabiliza...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nuclear factor erythroid 2-related factor 2
(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by
ChEMBL
Ligand
BDBM50498210
(CHEMBL3423015)
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Copy InChI
Affinity Data
Kd: 352nM
Assay Description:
Binding affinity to Keap1/Nrf2 complex (unknown origin) by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kelch-like ECH-associated protein 1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50498210
(CHEMBL3423015)
Copy SMILES
Copy InChI
Affinity Data
Kd: 352nM
Assay Description:
Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI