Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  238nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  4.11E+4nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed