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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
Cytosol aminopeptidase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50046325
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
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Affinity Data
Ki: 1.70E+4nM
Assay Description:
Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...
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Target Info
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Target
Aminopeptidase N
(Sus scrofa (Pig))
TBA
Curated by
ChEMBL
Ligand
BDBM50046325
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
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Affinity Data
Ki: 2.00E+5nM
Assay Description:
Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...
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Target Info
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3D Structure (crystal)
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Target
Aminopeptidase N
(Sus scrofa (Pig))
TBA
Curated by
ChEMBL
Ligand
BDBM50046325
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
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Affinity Data
Ki: 5.00E+5nM
Assay Description:
Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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CHEMBL
MMDB
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PC sid
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Article
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3D Structure (crystal)
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Target
Aminopeptidase B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50046325
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
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Affinity Data
IC50: 4.20E+3nM
Assay Description:
Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetry
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Target Info
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Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50046325
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI