Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL

LigandBDBM50492323(CHEMBL2402205)Copy SMILESCopy InChI

Affinity DataIC50:  33nMAssay Description:Displacement of MR121-Nrf2 from human N-terminal His-tagged Kelch-DC domain of Keap1 (321 to 609) expressed in Escherichia coli BL21 (DE3) after 40 m...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoKEGGPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

LigandBDBM50492323(CHEMBL2402205)Copy SMILESCopy InChI

Affinity DataKd:  29nMAssay Description:Binding affinity to Keap1/Nrf2 complex (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoKEGGPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI