Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Gsk

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gsk

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
Affinity DataKi:  140nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Gsk

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
Affinity DataKi:  310nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gsk

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
Affinity DataKi:  2.60E+3nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Gsk

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed