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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Cathepsin K
(Homo sapiens (Human))
Gsk
Ligand
BDBM19798
(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
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Affinity Data
Ki: 140nM ΔG°: -38.7kJ/mole
pH: 5.5 T: 2°C
Assay Description:
Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin K
(Homo sapiens (Human))
Gsk
Ligand
BDBM19798
(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
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Affinity Data
Ki: 140nM
Assay Description:
Inhibitory activity against human cysteine protease, cathepsin K.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Gsk
Ligand
BDBM19798
(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
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Affinity Data
Ki: 310nM
Assay Description:
Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Gsk
Ligand
BDBM19798
(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin B
(Homo sapiens (Human))
Gsk
Ligand
BDBM19798
(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)
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Affinity Data
Ki: >1.00E+4nM ΔG°: >-28.3kJ/mole
pH: 5.5 T: 2°C
Assay Description:
Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI