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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataKi:  56nMAssay Description:Irreversible inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant Human cathepsin L (18 to 333 residues) expressed in FreeStyle 293-F cells using Z-Leu-Arg-MCA peptide...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant Human cathepsin S (17 to 331 residues) expressed in FreeStyle 293-F cells using Z-Leu-Arg-MCA peptide...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His-tagged Human cathepsin B expressed in FreeStyle 293-F cells using Z-Leu-Arg-MCA peptide as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In DepthDetails PubMed