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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Cathepsin K
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Affinity Data
Ki: 0.00480nM
Assay Description:
Inhibition of Human cathepsin K
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Procathepsin L
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Affinity Data
Ki: 0.490nM
Assay Description:
Inhibitory activity of the compound against Human cathepsin L
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Rattus norvegicus)
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Affinity Data
Ki: 4.80nM
Assay Description:
Inhibitory activity of the compound against Rat cathepsin K
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Affinity Data
Ki: 14nM
Assay Description:
Inhibitory activity of the compound against Human cathepsin S
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Affinity Data
Ki: 100nM
Assay Description:
Inhibitory activity of the compound against Human cathepsin B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Affinity Data
IC50: 8.30nM
Assay Description:
Inhibition of human recombinant cathepsin S using Ac-KQLR-AMC as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
In vitro cell based assay for measuring the IC50 values of osteoblast resorption.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cathepsin K
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
In vitro IC50 value of the compound was measured using in situ cytochem assay.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cathepsin S
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50098576
(5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ...)
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Copy InChI
Affinity Data
IC50: 940nM
Assay Description:
Inhibition of cathepsin S in human Raji cells assessed as decrease in cell surface expression of MHC class 2/CLIP by flow cytometric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI