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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetRenin(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084627((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexyl...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:Inhibitory concentration against human plasma renin at pH 6.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084627((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexyl...)
Affinity DataIC50:  550nMAssay Description:Inhibitory concentration against cathepsin D..Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084627((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexyl...)
Affinity DataKon:  0.000280M-1s-1 Koff:  5.93s-1Assay Description:Component acylation rate constant by the compound against Renin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed