Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
Cathepsin K(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19885((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpip...)
Cathepsin K(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19884(N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpiperazi...)
IC50: 8nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Cathepsin S(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19884(N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpiperazi...)
Cathepsin B(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19885((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpip...)
Cathepsin B(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19884(N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpiperazi...)
IC50: 3.84E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Cathepsin S(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19885((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpip...)
IC50: 3.93E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Procathepsin L(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19884(N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpiperazi...)
Procathepsin L(Homo sapiens (Human))Merck Frosst Centre For Therapeutic Research
BDBM19885((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(4-methylpip...)
IC50: 6.27E+3nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair