Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Philipps-Universität Marburg

LigandBDBM97448(Aspartyl protease inhibitor, 14)Copy SMILESCopy InChI

Affinity DataIC50:  3.30E+3nMpH: 5.5Assay Description:Binding constants for inhibition of HIV protease were determined as previously described.More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Philipps-Universität Marburg

LigandBDBM97448(Aspartyl protease inhibitor, 14)Copy SMILESCopy InChI

Affinity DataIC50: >4.00E+4nMpH: 5.5Assay Description:Binding constants for inhibition of HIV protease were determined as previously described.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI