Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  890nMAssay Description:Inhibition of cathepsin S (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of cathepsin L (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of cathepsin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed