Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetLeukotriene C4 synthase(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50462326(CHEMBL4251024)
Affinity DataIC50:  30nMAssay Description:Inhibition of LTC4 synthase in LPS/fMLP-stimulated human monocytes assessed as decrease in cys-LT formation pre-incubated with LPS for 30 mins and la...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50462326(CHEMBL4251024)
Affinity DataIC50:  50nMAssay Description:Inhibition of FLAP in A23187-stimulated human neutrophils assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50462326(CHEMBL4251024)
Affinity DataIC50:  60nMAssay Description:Inhibition of 5-LO in A23187-stimulated human neutrophils assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50462326(CHEMBL4251024)
Affinity DataIC50:  70nMAssay Description:Inhibition of FLAP in A23187-stimulated human monocytes assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed