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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human))
Gazi University
Curated by
ChEMBL
Ligand
BDBM50462328
(CHEMBL4251469)
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Affinity Data
IC50: 50nM
Assay Description:
Inhibition of FLAP in A23187-stimulated human neutrophils assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Prostaglandin E synthase
(Homo sapiens (Human))
Gazi University
Curated by
ChEMBL
Ligand
BDBM50462328
(CHEMBL4251469)
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Affinity Data
IC50: 420nM
Assay Description:
Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell microsomal fractions assessed as reduction in PGE2 production preincubated for 15 mins fo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Gazi University
Curated by
ChEMBL
Ligand
BDBM50462328
(CHEMBL4251469)
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Affinity Data
IC50: 600nM
Assay Description:
Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 incubated for 15 mins prior to prewarming for 30 secs followed by CaCl2+ and ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Leukotriene C4 synthase
(Homo sapiens (Human))
Gazi University
Curated by
ChEMBL
Ligand
BDBM50462328
(CHEMBL4251469)
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Affinity Data
IC50: 6.19E+3nM
Assay Description:
Inhibition of human LTC4 synthase expressed in HEK293 cell microsomes preincubated for 10 mins followed by LTA4-methyl ester addition and measured af...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI