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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50202473(CHEMBL3954390)
Affinity DataIC50:  12nMAssay Description:Inhibition of FLAP in human monocytes assessed as suppression of fMLP/LPS-stimulated cys-LT formation preincubated for 15 mins measured after 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50202473(CHEMBL3954390)
Affinity DataIC50:  26nMAssay Description:Inhibition of FLAP in human monocytes assessed as suppression of A23187-stimulated 5-LO product formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50202473(CHEMBL3954390)
Affinity DataIC50:  35nMAssay Description:Inhibition of FLAP in human monocytes assessed as suppression of A23187-stimulated 5-LO product formation using 10 uM arachidonic acid as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50202473(CHEMBL3954390)
Affinity DataIC50:  70nMAssay Description:Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed