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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Histamine H4 receptor
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM189351
(4-(4-Methylpiperazin-1-yl)-6-(2-methylpropyl)-1,3,...)
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Affinity Data
Ki: 529nM
Assay Description:
Displacement of [3H]-histamine from recombinant human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2/Gbeta1gamma2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM189351
(4-(4-Methylpiperazin-1-yl)-6-(2-methylpropyl)-1,3,...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.26E+3nM ΔG°: -27.0kJ/mole
pH: 7.4 T: 2°C
Assay Description:
Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM189351
(4-(4-Methylpiperazin-1-yl)-6-(2-methylpropyl)-1,3,...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.26E+3nM
Assay Description:
Displacement of [3H]histamine from human H4R expressed in Sf9 cell membranes co-expressed with G protein Gai2 and Gb1gamma2 incubated for 60 mins by ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI