Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393887(CHEMBL2158257)
Affinity DataKi:  240nMAssay Description:Inhibition of human cathepsin D using DAB-CYL-Glu-ArG-Nle-Phe-Leu-Ser-Phe-Pro-EDANS incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393887(CHEMBL2158257)
Affinity DataIC50:  19nMAssay Description:Inhibition of BACE1 in human HEK cells expressing APP Swedish mutant assessed as reduction in amyloid beta40 level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393887(CHEMBL2158257)
Affinity DataIC50:  22nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393887(CHEMBL2158257)
Affinity DataIC50:  150nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Eu-EVNLDAEFK as substrate incubated for 30 mins prior to substrate addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed