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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
Affinity DataKi:  3.80E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
Affinity DataKi: >7.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
Affinity DataIC50:  5.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407518(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity for Beta-2 adrenergic receptor was assessed from effect on relaxation of guinea pig trachea.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407518(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
Affinity DataEC50:  6.30E+4nMAssay Description:Activity for beta 3-adrenoceptor was assessed from effect on stimulation of lipolysis in rat adipocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407518(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
Affinity DataEC50:  2.20E+3nMAssay Description:Activity for Beta-1 adrenergic receptor was assessed from ability to stimulate contractions in isolated guinea pig atrium.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed