Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 173 hits in this display
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Ki: 2.40nMAssay Description:Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
Ki: 46nMAssay Description:Displacement of [3H]-CGP-12177 from human beta2-adrenergic receptor expressed in CHO cells after 60 mins by radioligand competition binding assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Ki: 192nMAssay Description:Displacement of [3H]-CGP-12177 from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Ki: 670nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Ki: 676nMAssay Description:Binding Affinity against human beta-2 adrenergic receptor expressed in Chinese hamster ovary(CHO) cells was measured by using [125I]ICYP radioligandMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Ki: 1.59E+3nMAssay Description:Binding Affinity against human Beta-1 adrenergic receptor expressed in Chinese hamster ovary(CHO) cells was measured by using [125I]ICYP radioligandMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Ki: 1.86E+4nMAssay Description:Binding Affinity against human Beta-3 adrenergic receptor expressed in Chinese hamster ovary(CHO) cells was measured by using [125I]ICYP radioligandMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
IC50: 0.100nMAssay Description:Agonistic activity for Beta-2 adrenergic receptor was assessed by it's inhibitory effect on spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
IC50: 0.100nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. IC50, the mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
IC50: 325nMAssay Description:The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.More data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
IC50: 600nMAssay Description:Compound was evaluated for its binding affinity towards beta-1 adrenergic receptor in rat heart membrane by displacing [125I]- iodocyanopindololMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
IC50: 1.00E+3nMAssay Description:Compound was evaluated for its binding affinity towards beta-2 adrenergic receptor in rat soleus membrane by displacing(-)-isoproterenol (50 microM)More data for this Ligand-Target Pair
BDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
BDBM34652((+)-ISOPROTERENOL (+)-BITARTRATE SALT | 2,3-bis(ox...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
IC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 6nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM50407518(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 3.20nMAssay Description:Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.160nMAssay Description:Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP productionChecked by AuthorMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 2nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 2nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 129nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in DU145 cells assessed as increase in cAMP accumulationMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 2nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.0840nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.970nMAssay Description:Agonistic activity was assessed by measuring cAMP accumulation in CHO cell lines expressing cloned human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 40nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as intracellular cAMP accumulation after 1 hrMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Kd: 25nMAssay Description:Agonist activity at adrenergic beta2 receptor in Hartley guinea pig tracheal ring at basal tone assessed as bronchorelaxation activityMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 86nMAssay Description:Agonist activity at human recombinant beta3-adrenergic receptor expressed in CHO cells assessed as increase of cAMP level after 30 minsMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.970nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.0840nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.970nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.840nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 120nMAssay Description:Agonist activity at PK-tagged beta2 receptor (unknown origin) transfected in HEK293 cells after 90 mins by beta-arrestin assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 32nMAssay Description:Agonist activity at guinea pig trachea beta2-adrenergic receptor assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 32nMAssay Description:Agonist activity at guinea pig trachea beta2-adrenergic receptor assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 31.6nMAssay Description:Agonist activity at beta2 adrenoceptor in guinea pig assessed as relaxation of histamine-induced tracheal ring contractionMore data for this Ligand-Target Pair
BDBM50407518(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
EC50: 2.20E+3nMAssay Description:Activity for Beta-1 adrenergic receptor was assessed from ability to stimulate contractions in isolated guinea pig atrium.More data for this Ligand-Target Pair
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
EC50: 2.20nMAssay Description:Activity for Beta-1 adrenergic receptor was assessed from ability to stimulate contractions in isolated guinea pig atrium.More data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 3.90nMAssay Description:Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as [3H]cAMP levels by radiolabeled ligand based assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407518(ISOPROTERENOL | L-ISOPRENALINE | LEVISOPRENALINE)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 7nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 1.5nMAssay Description:Compound was evaluated for its binding affinity towards Beta-1 adrenergic receptor in rat heart membrane by displacing [125I]- iodocyanopindololMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 3.20nMAssay Description:Agonist activity at recombinant human beta1 adrenergic receptor expressed in CHO cells assessed as accumulation of cyclic AMP after 30 minsMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 13nMAssay Description:Agonist activity at recombinant human beta2 adrenergic receptor expressed in CHO cells assessed as accumulation of cyclic AMP after 30 minsMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 86nMAssay Description:Agonist activity at recombinant human beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cyclic AMP after 30 minsMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.316nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 3.20nMAssay Description:Agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 54nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.200nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulationMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 3.20nMAssay Description:Agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.316nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM50407517((-)ISOPROTERENOL | CHEMBL1160723 | US9492405, 27)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Kd: 130nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Kd: 130nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Kd: 740nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 1.20nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium influx by measuri...More data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 7.90nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal smooth muscle assessed as inhibition of histamine-induced tracheal smooth muscle...More data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 0.0550nMAssay Description:Agonist activity at human beta2 adrenoreceptor overexpressed in human HEK293 cells assessed as cAMP accumulation incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
EC50: 1.5nMAssay Description:Agonist activity at human beta1 adrenoreceptor overexpressed in human HEK293 cells assessed as cAMP accumulation incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
BDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
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