Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM50341312((1R,5R,8R)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
BDBM50341311((+/-)-isopropyl 8-(5-methyl-6-(2-methylpyridin-3-y...)
Ki: 1.60E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
BDBM50341313((1S,5S,8S)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
Ki: 2.27E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
BDBM50341312((1R,5R,8R)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
EC50: 740nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
BDBM50341311((+/-)-isopropyl 8-(5-methyl-6-(2-methylpyridin-3-y...)
EC50: 1.24E+3nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
BDBM50341313((1S,5S,8S)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
EC50: 2.07E+3nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair