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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50396141
(CHEMBL2171708)
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Affinity Data
Ki: 20nM
Assay Description:
Agonist activity at GPR119
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
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Affinity Data
Ki: 33nM
Assay Description:
Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 33nM
Assay Description:
Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 125nM
Assay Description:
Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 125nM
Assay Description:
Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 65nM
Assay Description:
Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 227nM
Assay Description:
Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 228nM
Assay Description:
Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50341310
(CHEMBL1766082 | Isopropyl 9-anti-({5-Methyl-6-[(2-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI