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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343442(CHEMBL1775179 | isopropyl 4-(1-(2-fluoro-4-(methyl...)
Affinity DataKi:  100nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343442(CHEMBL1775179 | isopropyl 4-(1-(2-fluoro-4-(methyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343442(CHEMBL1775179 | isopropyl 4-(1-(2-fluoro-4-(methyl...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343442(CHEMBL1775179 | isopropyl 4-(1-(2-fluoro-4-(methyl...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human GPR119 expressed in human HEK293 cells assessed as increase in adenylate cyclase activationMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343442(CHEMBL1775179 | isopropyl 4-(1-(2-fluoro-4-(methyl...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair